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Performance dependence of hybrid x-ray computed tomography/fluorescence molecular tomography on the optical forward problem.
J. Opt. Soc. Am. A-Opt. Image Sci. Vis. 26, 919-923 (2009)
Hybrid imaging systems combining x-ray computed tomography (CT) and fluorescence tomography can improve fluorescence imaging performance by incorporating anatomical x-ray CT information into the optical inversion problem. While the use of image priors has been investigated in the past, little is known about the optimal use of forward photon propagation models in hybrid optical systems. In this paper, we explore the impact on reconstruction accuracy of the use of propagation models of varying complexity, specifically in the context of these hybrid imaging systems where significant structural information is known a priori. Our results demonstrate that the use of generically known parameters provides near optimal performance, even when parameter mismatch remains.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
least-squares; reconstruction; regularization; breast; mri
ISSN (print) / ISBN
0740-3232
e-ISSN
1520-8532
Quellenangaben
Volume: 26,
Issue: 4,
Pages: 919-923
Publisher
OMICS
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)