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Open Access Green as soon as Postprint is submitted to ZB.
Toward cheap disposable sensing devices for biological assays.
IEEE Trans. Nanotechnol. 9, 527-532 (2010)
There is a significant demand for small, portable, and inexpensive analytical devices, which can be used in a wide range of sensing applications (e.g., food monitoring, detection of chemical, biological poisoning agents, environmental monitoring, medical diagnostics, military defense, etc.). Sensors based on organic semi-conducting polymers, which are suitable for large-area, low-cost, flexible, and eventually single-use throwaway electronics, provide a unique opportunity in that sense. We report on low-operating voltage organic field-effect transistor devices, which can be used as sensors in electrolytes and liquid media, using a biofunctionalized, biocompatible, regioregular poly(3-hexylthiophene) semiconducting layer. Measurements in electrolytes and complex media relevant for cell analysis have shown that the devices can be directly used as ion-sensitive transducers and are suitable for in vitro biosensing applications. With the demonstration of biocompatible semiconducting polymeric devices, we have overcome a substantial hurdle for the realization of low-cost and mass-produced sensors, opening new possibilities of biological sensing using organic devices.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Biomaterials and biological interfaces; biosensors; Organic devices; Poly(3-hexylthiophene) (P3HT); Polymers
ISSN (print) / ISBN
1536-125X
e-ISSN
1941-0085
Quellenangaben
Volume: 9,
Issue: 5,
Pages: 527-532
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Radiation Protection (ISS)