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Open Access Green as soon as Postprint is submitted to ZB.
Adjoint time domain method for fluorescent imaging in turbid media.
Appl. Opt. 47, 2303-2311 (2008)
Application of adjoint time domain methods to the inverse problem in 3D fluorescence imaging is a novel approach. We demonstrate the feasibility of this approach experimentally on the basis of a time gating technique completely in the time domain by using a small number of time windows. The evolution of the fluorescence energy density function inside a highly scattering cylinder was reconstructed together with optical parameters. Reconstructed energy density was used in localizing two fluorescent tubes. Relatively accurate reconstruction demonstrates the effectiveness and the potential of the proposed technique.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
optical tomography; scattering media; data-acquisition; lifetime; boundary; contrast; tissue; system
ISSN (print) / ISBN
0003-6935
e-ISSN
1539-4522
Journal
Applied Optics
Quellenangaben
Volume: 47,
Issue: 13,
Pages: 2303-2311
Publisher
Optical Society of America (OSA)
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)