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Schramm, K.-W.

Environmental Impact Assessment (EIA): Equilibrium Fugacity Calculations and Worst Case Approach.

Chemosphere 28, 2151-2171 (1994)

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Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.

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A mathematical model UNITRISK which can be used for screening purposes and risk ranking was set up to calculate relative risk values of single chemicals and mixtures of chemicals towards single or mixtures of organisms via contamination of air, water, soil and food dose. The concentration values are calculated by applying the fugacity concept or a dose must be defined. The dose-response is assumed to be linear versus concentration and degradative processes are not considered which is the worst case. The assumption that equilibria between the environmental phases exist is simplifying the model and is also representing the worst case. A mean risk factor is calculated which is 1 if the endpoint values (LC₅₀, LD₅₀, ADI, etc.) are exceeded for the investigated organisms and man.

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