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Large-scale production of mouse phenotypes : the search for animal models for inherited diseases in humans.
Brief. Bioinform. 2, 170-180 (2001)
This paper is aimed principally at bioinformaticians and biologists as an introduction to recent advances in mouse mutagenesis, concentrating on genome-wide screens utilising the powerful mutagen N-ethyl-N-nitroso-urea (ENU). It contains a brief background to the underlying genetics as well as details of the practical aspects of organisation and data capture for such projects.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Ethyl-N-nitrosourea phenotype mouse models functional genomics
ISSN (print) / ISBN
1467-5463
e-ISSN
1477-4054
Journal
Briefings in Bioinformatics
Quellenangaben
Volume: 2,
Issue: 2,
Pages: 170-180
Publisher
Oxford University Press
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Experimental Genetics (IEG)