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Ionizing radiation effects on cells, organelles and tissues on proteome level.

Adv. Exp. Med. Biol. 990, 37-48 (2013)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
This chapter will review the proteome alterations induced by ionizing radiation in cellular systems or using animal models with whole body or localised exposure. The recent developments in qualitative and quantitative proteome analysis using formalin-fixed paraffin-embedded material from radiobiology archives will be illustrated. The development of promising protein targets to be used as radiation biomarkers in future molecular epidemiology studies is described.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Biomarker ; Cardiovascular System ; Ea.hy926 ; Endothelial Cells ; Formalin-fixed ; Heart ; Ionizing Radiation ; Lymphocytes ; Mitochondria ; Nucleolar Proteome ; Paraffin-embedded ; Proteome; Oxidative Stress; Cardiovascular-diseases; Endothelial-cells; Breast-cancer; Long-term; Mortality Experience; Gamma-irradiation; Heart-disease; Follow-up; Exposure
Language english
Publication Year 2013
HGF-reported in Year 2013
ISSN (print) / ISBN 0065-2598
Quellenangaben Volume: 990, Issue: , Pages: 37-48 Article Number: , Supplement: ,
Publisher Springer
Publishing Place New York
Reviewing status Peer reviewed
POF-Topic(s) 30202 - Environmental Health
Research field(s) Radiation Sciences
PSP Element(s) G-500200-001
PubMed ID 23378001
Scopus ID 84879022334
Scopus ID 84893112060
Erfassungsdatum 2013-03-06