Ionizing radiation effects on cells, organelles and tissues on proteome level.
    
    
        
    
    
        
        Adv. Exp. Med. Biol. 990, 37-48 (2013)
    
    
 	
    
	
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	    This chapter will review the proteome alterations induced by ionizing radiation in cellular systems or using animal models with whole body or localised exposure. The recent developments in qualitative and quantitative proteome analysis using formalin-fixed paraffin-embedded material from radiobiology archives will be illustrated. The development of promising protein targets to be used as radiation biomarkers in future molecular epidemiology studies is described.
	
	
	    
	
       
      
	
	    
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        Publication type
        Article: Journal article
    
 
    
        Document type
        Scientific Article
    
 
    
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        Keywords
        Biomarker ; Cardiovascular System ; Ea.hy926 ; Endothelial Cells ; Formalin-fixed ; Heart ; Ionizing Radiation ; Lymphocytes ; Mitochondria ; Nucleolar Proteome ; Paraffin-embedded ; Proteome; Oxidative Stress; Cardiovascular-diseases; Endothelial-cells; Breast-cancer; Long-term; Mortality Experience; Gamma-irradiation; Heart-disease; Follow-up; Exposure
    
 
    
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        english
    
 
    
        Publication Year
        2013
    
 
    
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        2013
    
 
    
    
        ISSN (print) / ISBN
        0065-2598
    
 
    
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	    Volume: 990,  
	    Issue: ,  
	    Pages: 37-48 
	    Article Number: ,  
	    Supplement: ,  
	
    
 
    
        
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            Springer
        
 
        
            Publishing Place
            New York
        
 
	
        
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        Reviewing status
        Peer reviewed
    
 
     
    
        POF-Topic(s)
        30202 - Environmental Health
    
 
    
        Research field(s)
        Radiation Sciences
    
 
    
        PSP Element(s)
        G-500200-001
    
 
    
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        Erfassungsdatum
        2013-03-06