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Open Access Green as soon as Postprint is submitted to ZB.
Ionizing radiation effects on cells, organelles and tissues on proteome level.
Adv. Exp. Med. Biol. 990, 37-48 (2013)
This chapter will review the proteome alterations induced by ionizing radiation in cellular systems or using animal models with whole body or localised exposure. The recent developments in qualitative and quantitative proteome analysis using formalin-fixed paraffin-embedded material from radiobiology archives will be illustrated. The development of promising protein targets to be used as radiation biomarkers in future molecular epidemiology studies is described.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Biomarker ; Cardiovascular System ; Ea.hy926 ; Endothelial Cells ; Formalin-fixed ; Heart ; Ionizing Radiation ; Lymphocytes ; Mitochondria ; Nucleolar Proteome ; Paraffin-embedded ; Proteome; Oxidative Stress; Cardiovascular-diseases; Endothelial-cells; Breast-cancer; Long-term; Mortality Experience; Gamma-irradiation; Heart-disease; Follow-up; Exposure
ISSN (print) / ISBN
0065-2598
Quellenangaben
Volume: 990,
Pages: 37-48
Publisher
Springer
Publishing Place
New York
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Radiation Biology (ISB)