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Open Access Green as soon as Postprint is submitted to ZB.
Failure of omalizumab and successful control with ketotifen in a patient with vibratory angio-oedema.
Clin. Exp. Dermatol. 38, 151-153 (2013)
Vibratory angio-oedema is a rare form of physical urticaria characterized by pruriginous weals and angio-oedema at the site of exposure to vibration. Severe treatment-resistant disease can occur, and is associated with significant disability. Therapy with omalizumab, a monoclonal IgG anti-IgE antibody, has been shown to be successful in several types of physical urticaria. We report a patient with vibratory angio-oedema for whom all standard treatments for urticaria, including omalizumab, failed to show a clinical benefit. Finally, ketotifen was tried, and unexpectedly reduced symptoms significantly. Ketotifen may thus represent a therapeutic option in patients with treatment-resistant vibratory angio-oedema.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Urticaria
ISSN (print) / ISBN
0307-6938
e-ISSN
1365-2230
Quellenangaben
Volume: 38,
Issue: 2,
Pages: 151-153
Publisher
Wiley
Reviewing status
Peer reviewed
Institute(s)
Institute for Allergy Research (IAF)