Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
The Ste20 kinase misshapen is essential for the invasive behaviour of ovarian epithelial cells in Drosophila.
EMBO Rep. 11, 943-949 (2010)
Stationary-to-migratory transitions of epithelial cells have a key role in development and tumour progression. Border cell migration is a powerful system in which to investigate this transition in living organisms. Here, we identify the Ste20-like kinase misshapen (msn) as a novel regulator of border-cell migration in Drosophila. Expression of msn in border cells is independent of the transcription factor slow border cells and of inputs from all pathways that are known to control border-cell migration. The msn gene functions to modulate the levels and/or distribution of Drosophila E-cadherin to promote the invasive migratory behaviour of border cells.
Impact Factor
Scopus SNIP
Scopus
Cited By
Cited By
Altmetric
0.000
1.170
20
Annotations
Special Publikation
Hide on homepage
Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2010
HGF-reported in Year
0
ISSN (print) / ISBN
1469-221X
e-ISSN
1469-3178
Journal
EMBO Reports
Quellenangaben
Volume: 11,
Issue: 12,
Pages: 943-949
Publisher
EMBO Press
Reviewing status
Peer reviewed
POF-Topic(s)
30204 - Cell Programming and Repair
Research field(s)
Stem Cell and Neuroscience
PSP Element(s)
G-500100-001
PubMed ID
21102643
Erfassungsdatum
2010-12-31