PuSH - Publication Server of Helmholtz Zentrum München

Eslami, A. ; Karamalis, A.* ; Katouzian, A.* ; Navab, N.*

Segmentation by retrieval with guided random walks: Application to left ventricle segmentation in MRI.

Med. Image Anal. 17, 236-253 (2013)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
In this paper, a new segmentation framework with prior knowledge is proposed and applied to the left ventricles in cardiac Cine MRI sequences. We introduce a new formulation of the random walks method, coined as guided random walks, in which prior knowledge is integrated seamlessly. In comparison with existing approaches that incorporate statistical shape models, our method does not extract any principal model of the shape or appearance of the left ventricle. Instead, segmentation is accompanied by retrieving the closest subject in the database that guides the segmentation the best. Using this techniques, rare cases can also effectively exploit prior knowledge from few samples in training set. These cases are usually disregarded in statistical shape models as they are outnumbered by frequent cases (effect of class population). In the worst-case scenario, if there is no matching case in the database to guide the segmentation, performance of the proposed method reaches to the conventional random walks, which is shown to be accurate if sufficient number of seeds is provided. There is a fast solution to the proposed guided random walks by using sparse linear matrix operations and the whole framework can be seamlessly implemented in a parallel architecture. The method has been validated on a comprehensive clinical dataset of 3D+t short axis MR images of 104 subjects from 5 categories (normal, dilated left ventricle, ventricular hypertrophy, recent myocardial infarction, and heart failure). The average segmentation errors were found to be 1.54 mm for the endocardium and 1.48 mm for the epicardium. The method was validated by measuring different algorithmic and physiologic indices and quantified with manual segmentation ground truths, provided by a cardiologist.
Altmetric
Additional Metrics?
[➜Log in]
Edit extra informations Login
Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Cardiac Cine Mri ; Segmentation By Retrieval ; Random Walks ; Left Ventricle Segmentation ; Guided Random Walks; Magnetic-resonance Images ; Cardiac Mri ; Cine-mri ; Automatic Segmentation ; Graph Cuts ; Model ; Deformation ; Extraction ; Recovery ; Heart
ISSN (print) / ISBN 1361-8415
e-ISSN 1361-8415
Journal Medical Image Analysis
Quellenangaben Volume: 17, Issue: 2, Pages: 236-253 Article Number: , Supplement: ,
Publisher Elsevier
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Computational Biology (ICB)