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Open Access Green as soon as Postprint is submitted to ZB.
MRT-gestützte Thermometrie in der regionalen Tiefenhyperthermie und interstitiellen Laserthermotherapie.
Radiologe 44, 310-319 (2004)
Purpose To demonstrate the potential of quantitative MRI-assisted thermometry for the treatment of tumor patients with regional hyperthermia (RHT) and interstitial laser thermotherapy (ILTT). Methods Two patients and seven tissue samples were investigated using the T1-relaxation time and the chemical shift of the proton resonance frequency (PRF) as temperature sensitive MRI-parameters at 0.2 and 1.5 T. Thermotherapy was applied using either a dedicated MRI-hyperthermia hybrid system or a temperature controlled laser with 830 nm. Results Both patients were treated successfully showing clinical benefit. T1 and PRF are depending on the applied thermotherapy method and on the MR-system suitable for MRI-assisted thermometry. The clinical application based on phantom results is not necessarily adequate. Conclusion Clinical application and phantom experiments of RHT and ILTT show the potential of MRI-assisted thermometry for further improvement of both minimal invasive thermotherapy methods. Further investigations concerning optimization of the MRI-techniques, the influence of perfusion or the determination of threshold values are necessary.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Magnetic resonance imaging (MRI) - Thermometry - Thermotherapy - Regional hyperthermia - Interstitial laser thermotherapy
ISSN (print) / ISBN
0033-832X
e-ISSN
1432-2102
Journal
Radiologe, Der
Quellenangaben
Volume: 44,
Issue: 4,
Pages: 310-319
Publisher
Springer
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
CCG Tumor Therapy with Hyperthermia (IMI-KTH)