Home
Login
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
DOI
PMC
 |
|
as soon as is submitted to ZB.
Perspectives of a systems biology of the brain: The big data conundrum understanding psychiatric diseases.
Pharmacopsychiatry 46, S2-S9 (2013)
Psychiatric diseases provoke human tragedies. Asocial behaviour, mood imbalance, uncontrolled affect, and cognitive malfunction are the price for the biological and social complexity of neurobiology. To understand the etiology and to influence the onset and progress of mental diseases remains of upmost importance, but despite the much improved care for the patients, more then 100 years of research have not succeeded to understand the basic disease mechanisms and enabling rationale treatment. With the advent of the genome based technologies, much hope has been created to join the various dimension of -omics data to uncover the secrets of mental illness. Big Data as generated by -omics do not come with explanations. In this essay, I will discuss the inherent, not well understood methodological foundations and problems that seriously obstacle in striving for a quick success and may render lucky strikes impossible.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Mental Disease ; Brain Imaging ; Complex Genetics ; Epistemology; Schizophrenia ; Illness ; Network ; Science
ISSN (print) / ISBN
0031-7098
e-ISSN
1439-0795
Journal
Pharmacopsychiatry
Quellenangaben
Volume: 46,
Pages: S2-S9
Publisher
Thieme
Publishing Place
Stuttgart
Reviewing status
Peer reviewed