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Raster-scan optoacoustic mesoscopy in the 25-125 MHz range.
Opt. Lett. 38, 2472-2474 (2013)
We developed a raster-scan acoustic resolution broadband optoacoustic mesoscopy system and investigated the imaging performance using ultrasonic frequencies up to 125 MHz. The developed system achieves 7 μm axial resolution and transverse resolution of 30 μm reaching depths of at least 5 mm. This unprecedented performance is achieved by operating at out-of-focus ultrasonic detection and tomographic reconstruction. We demonstrate the limits reached due to the width of the laser pulse employed and showcase the technique on drosophila fly and drosophila pupae ex vivo.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
In-vivo ; Photoacoustic Microscopy ; High-resolution ; Tomography ; Deep
Language
english
Publication Year
2013
HGF-reported in Year
2013
ISSN (print) / ISBN
0146-9592
e-ISSN
1539-4794
Journal
Optics Letters
Quellenangaben
Volume: 38,
Issue: 14,
Pages: 2472-2474
Publisher
Optical Society of America (OSA)
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-505500-001
WOS ID
WOS:000321770900033
Erfassungsdatum
2013-07-29