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Trajectory optimization for intra-operative nuclear tomographic imaging.
Med. Image Anal. 17, 723-731 (2013)
Diagnostic nuclear imaging modalities like SPECT typically employ gantries to ensure a densely sampled geometry of detectors in order to keep the inverse problem of tomographic reconstruction as well-posed as possible. In an intra-operative setting with mobile freehand detectors the situation changes significantly, and having an optimal detector trajectory during acquisition becomes critical. In this paper we propose an incremental optimization method based on the numerical condition of the system matrix of the underlying iterative reconstruction method to calculate optimal detector positions during acquisition in real-time. The performance of this approach is evaluated using simulations. A first experiment on a phantom using a robot-controlled intra-operative SPECT-like setup demonstrates the feasibility of the approach.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Image reconstruction (iterative); Medical robotics; Nuclear imaging; Optimization; Sentinel Node Biopsy ; Freehand Spect ; Ultrasound ; Accuracy ; Cancer
ISSN (print) / ISBN
1361-8415
e-ISSN
1361-8415
Journal
Medical Image Analysis
Quellenangaben
Volume: 17,
Issue: 7,
Pages: 723-731
Publisher
Elsevier
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Computational Biology (ICB)