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Weighted model-based optoacoustic reconstruction in acoustic scattering media.
Phys. Med. Biol. 58, 5555-5566 (2013)
Model-based optoacoustic inversion methods are capable of eliminating image artefacts associated with the widely adopted back-projection reconstruction algorithms. Yet, significant image artefacts might also occur due to reflections and scattering of optoacoustically-induced waves from strongly acoustically-mismatched areas in tissues. Herein, we modify the model-based reconstruction methodology to incorporate statistically-based weighting in order to minimize these artefacts. The method is compared with another weighting procedure termed half-image reconstruction, yielding generally better results. The statistically-based weighting is subsequently verified experimentally, attaining quality improvement of the optoacoustic image reconstructions in the presence of acoustic mismatches in tissue phantoms and small animals ex-vivo.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Image-reconstruction ; Thermoacoustic Tomography ; Algorithm
ISSN (print) / ISBN
0031-9155
e-ISSN
1361-6560
Journal
Physics in Medicine and Biology
Quellenangaben
Volume: 58,
Issue: 16,
Pages: 5555-5566
Publisher
Institute of Physics Publishing (IOP)
Publishing Place
Bristol
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)