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Weighted model-based optoacoustic reconstruction in acoustic scattering media.

Phys. Med. Biol. 58, 5555-5566 (2013)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Model-based optoacoustic inversion methods are capable of eliminating image artefacts associated with the widely adopted back-projection reconstruction algorithms. Yet, significant image artefacts might also occur due to reflections and scattering of optoacoustically-induced waves from strongly acoustically-mismatched areas in tissues. Herein, we modify the model-based reconstruction methodology to incorporate statistically-based weighting in order to minimize these artefacts. The method is compared with another weighting procedure termed half-image reconstruction, yielding generally better results. The statistically-based weighting is subsequently verified experimentally, attaining quality improvement of the optoacoustic image reconstructions in the presence of acoustic mismatches in tissue phantoms and small animals ex-vivo.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Image-reconstruction ; Thermoacoustic Tomography ; Algorithm
ISSN (print) / ISBN 0031-9155
e-ISSN 1361-6560
Quellenangaben Volume: 58, Issue: 16, Pages: 5555-5566 Article Number: , Supplement: ,
Publisher Institute of Physics Publishing (IOP)
Publishing Place Bristol
Non-patent literature Publications
Reviewing status Peer reviewed