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Bühler, A. ; Dean-Ben, X.L. ; Razansky, D. ; Ntziachristos, V.

Volumetric optoacoustic imaging with multi-bandwidth deconvolution.

IEEE Trans. Med. Imaging 33, 814-821 (2014)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Optoacoustic (photoacoustic) imaging based on cylindrically focused one-dimensional transducer arrays comes with powerful characteristics in visualizing optical contrast. Parallel reading of multiple detectors arranged around a tissue crosssection enables capturing data for generating images of this plane within micro-seconds. Dedicated small animals scanners and handheld systems using one-dimensional cylindrically focused ultrasound transducer arrays have demonstrated real-time crosssectional imaging and high in-plane resolution. Yet, the resolution achieved along the axis perpendicular to the focal plane, i.e. the elevation resolution, is determined by the focusing capacities of the detector and is typically lower than the in-plane resolution. Herein, we investigated whether deconvolution of the sensitivity field of the transducer could lead to tangible image improvements. We showcase the findings on experimental measurements from phantoms and animals and discuss the features and the limitations of the approach in improving resolution along the elevation dimension.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Cross-sectional Imaging ; Optoacoustic Tomography ; Out-of-plane Artefacts ; Photoacoustic Tomography ; Three-dimensional (3-d) Imaging; Photoacoustic Tomography; In-vivo; Computed-tomography; Small Animals; Video-rate; Model; Reconstruction; Microscopy; Transducer; System
ISSN (print) / ISBN 0278-0062
e-ISSN 1558-254X
Journal IEEE Transactions on Medical Imaging
Quellenangaben Volume: 33, Issue: 4, Pages: 814-821 Article Number: , Supplement: ,
Publisher Institute of Electrical and Electronics Engineers (IEEE)
Publishing Place New York, NY [u.a.]
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)