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Molecular profiling for the identification of new biomarkers in smokers and cancer patients.
Cancer Genomics Proteomics 4, 349-358 (2007)
Smoking is associated with different serious diseases, including cancer. The fact that only a minority of smokers develops tobacco-associated diseases suggests the contribution of other individual factors, which are still far from understood. New technologies that can be referred to as 'molecular profiling' allow for investigating the deregulation of thousands of genes simultaneously. Numerous such studies have investigated in vitro and in vivo the effects of smoking in different cell types aiming at a better understanding of smoking-induced diseases and the detection of new biomarkers of exposure and harm. This review is a short survey of these investigations and how they have contributed to the detection of new biomarkers and to a better understanding of smoking-induced harm.
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Publication type
Article: Journal article
Document type
Review
ISSN (print) / ISBN
1109-6535
e-ISSN
1790-6245
Journal
Cancer Genomics & Proteomics
Quellenangaben
Volume: 4,
Issue: 5,
Pages: 349-358
Publisher
International Institute of Anticancer Research
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Research Unit Gene Vector (AGV)