Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
Publ. Version/Full Text
DOI
PMC
 |
Free by publisher |
Open Access Green as soon as Postprint is submitted to ZB.
Diabetes subphenotypes and metabolomics: The key to discovering laboratory markers for personalized medicine?
Clin. Chem. 59, 1294-1296 (2013)
Publ. Version/Full Text
DOI
PMC
For decades, glucose, hemoglobin A1c, insulin, and C peptide have been the laboratory tests of choice to detect and monitor diabetes (1). However, these tests do not identify individuals at risk for developing type 2 diabetes (T2Dm)4 (so-called prediabetic individuals and the subphenotypes therein), which would be a prerequisite for individualized prevention. Nor are these parameters suitable to identify T2Dm subphenotypes, a prerequisite for individualized therapeutic interventions. The oral glucose tolerance test (oGTT) is still the only means for the early and reliable identification of people in the prediabetic phase with impaired glucose tolerance (IGT). This procedure, however, is very time-consuming and expensive and is unsuitable as a screening method in a doctor′s office. Hence, there is an urgent need for innovative laboratory tests to simplify the early detection of alterations in glucose metabolism.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Editorial
ISSN (print) / ISBN
0009-9147
e-ISSN
1530-8561
Journal
Clinical Chemistry
Quellenangaben
Volume: 59,
Issue: 9,
Pages: 1294-1296
Publisher
American Association for Clinical Chemistry
Non-patent literature
Publications
Reviewing status
Peer reviewed