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LINE(1)s of evidence in HBV-driven liver cancer.
Cell Host Microbe 15, 249-250 (2014)
Hepatitis B virus (HBV) integration in hepatocellular carcinoma (HCC) is a poorly understood event. In a recent Cancer Cell paper, Lau et al. (2014) describe a HBV-human fusion transcript (HBx-LINE1) that functions as a lncRNA, influences the epithelial-mesenchymal transition, and correlates with reduced patient survival and tumor formation in mice.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Hepatocellular-carcinoma; Integration; Carcinogenesis; Dna
ISSN (print) / ISBN
1931-3128
e-ISSN
1934-6069
Journal
Cell Host & Microbe
Quellenangaben
Volume: 15,
Issue: 3,
Pages: 249-250
Publisher
Elsevier
Publishing Place
Cambridge
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Virology (VIRO)