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Heikenwälder, M. ; Protzer, U.

LINE(1)s of evidence in HBV-driven liver cancer.

Cell Host Microbe 15, 249-250 (2014)
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Hepatitis B virus (HBV) integration in hepatocellular carcinoma (HCC) is a poorly understood event. In a recent Cancer Cell paper, Lau et al. (2014) describe a HBV-human fusion transcript (HBx-LINE1) that functions as a lncRNA, influences the epithelial-mesenchymal transition, and correlates with reduced patient survival and tumor formation in mice.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Hepatocellular-carcinoma; Integration; Carcinogenesis; Dna
Language english
Publication Year 2014
HGF-reported in Year 2014
ISSN (print) / ISBN 1931-3128
e-ISSN 1934-6069
Journal Cell Host & Microbe
Quellenangaben Volume: 15, Issue: 3, Pages: 249-250 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Cambridge
Reviewing status Peer reviewed
Institute(s) Institute of Virology (VIRO)
POF-Topic(s) 30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
30203 - Molecular Targets and Therapies
Research field(s) Immune Response and Infection
PSP Element(s) G-551600-001
G-502700-003
PubMed ID 24629329
DOI 10.1016/j.chom.2014.02.015
WOS ID WOS:000333098600001
Erfassungsdatum 2014-03-26
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