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RNAither, an automated pipeline for the statistical analysis of high-throughput RNAi screens.
Bioinformatics 25, 678-679 (2009)
SUMMARY: We present RNAither, a package for the free statistical environment R which performs an analysis of high-throughput RNA interference (RNAi) knock-down experiments, generating lists of relevant genes and pathways out of raw experimental data. The library provides a quality assessment of the signal intensities, as well as a broad range of options for data normalization, different statistical tests for the identification of significant siRNAs, and a significance analysis of the biological processes involving corresponding genes. The results of the analysis are presented as a set of HTML pages. Additionally, all values and plots are available as either text files or pdf and png files. AVAILABILITY: http://bioconductor.org/
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2009
HGF-reported in Year
0
e-ISSN
1367-4811
Journal
Bioinformatics
Quellenangaben
Volume: 25,
Issue: 5,
Pages: 678-679
Publisher
Oxford University Press
Publishing Place
Oxford
Reviewing status
Peer reviewed
Institute(s)
Institute of Computational Biology (ICB)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-503800-001
PubMed ID
19168909
Erfassungsdatum
2009-12-31