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Open Access Green as soon as Postprint is submitted to ZB.
Severe pretreatment cerebral edema in newly diagnosed type 1 diabetes.
Horm. Res. Paediatr. 81, 285-288 (2014)
Introduction: Cerebral edema (CE) is a rare and dangerous complication of diabetic ketoacidosis. In typical cases, it may develop during several hours after the beginning of ketoacidosis therapy. Nevertheless, CE sometimes occurs before the start of any therapy - as for the patient in this report here. Case Report: We describe a 12-year-old girl with newly diagnosed type 1 diabetes, presenting with severe headache and disorientation. Diabetes-related symptoms were not reported by the family. Clinical investigation revealed signs of meningeal irritation and Kussmaul breathing. In the laboratory, severe ketoacidosis (pH 6.95) and hyperglycemia (blood glucose 20.9 mmmol/l) were found. Cranial computed tomography showed CE. The patient was treated with a very cautious fluid and insulin therapy and recovered within 3 days. MRI after recovery showed normal findings without residuals of CE. Conclusion: CE before any treatment of ketoacidosis is a very rare complication of type 1 diabetes. Early diagnosis and effective treatment are extremely important for the patient's outcome and prognosis.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Type 1 Diabetes ; Rapid Progression ; Neurological Symptoms ; Ketoacidosis ; Cerebral Edema; Risk-factors; Ketoacidosis; Children
ISSN (print) / ISBN
1663-2818
e-ISSN
1663-2826
Journal
Hormone Research in Paediatrics
Quellenangaben
Volume: 81,
Issue: 4,
Pages: 285-288
Publisher
Karger
Publishing Place
Basel
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes Research Type 1 (IDF)