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Hohmann, C.* ; Pinart, M.* ; Tischer, C.G. ; Gehring, U.* ; Heinrich, J. ; Kull, I.* ; Melén, E.* ; Smit, H.A.* ; Torrent, M.* ; Wijga, A.H.* ; Wickman, M.* ; Bachert, C.* ; Lødrup Carlsen, K.C.* ; Carlsen, K.H.* ; Bindslev-Jensen, C.* ; Eller, E.* ; Esplugues, A.* ; Fantini, M.P.* ; Annesi-Maesano, I.* ; Momas, I.* ; Porta, D.* ; Vassilaki, M.* ; Waiblinger, D.* ; Sunyer, J.* ; Antò, J.M.* ; Bousquet, J.* ; Keil, T.*

The development of the MeDALL core questionnaires for a harmonized follow-up assessment of eleven European birth cohorts on asthma and allergies.

Int. Arch. Allergy Immunol. 163, 215-224 (2014)
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Background: Numerous birth cohorts have been initiated in the world over the past 30 years using heterogeneous methods to assess the incidence, course and risk factors of asthma and allergies. The aim of the present work is to provide the stepwise proceedings of the development and current version of the harmonized MeDALL-Core Questionnaire (MeDALL-CQ) used prospectively in 11 European birth cohorts. Methods: The harmonization of questions was accomplished in 4 steps: (i) collection of variables from 14 birth cohorts, (ii) consensus on questionnaire items, (iii) translation and back-translation of the harmonized English MeDALL-CQ into 8 other languages and (iv) implementation of the harmonized follow-up. Results: Three harmonized MeDALL-CQs (2 for parents of children aged 4-9 and 14-18, 1 for adolescents aged 14-18) were developed and used for a harmonized follow-up assessment of 11 European birth cohorts on asthma and allergies with over 13,000 children. Conclusions: The harmonized MeDALL follow-up produced more comparable data across different cohorts and countries in Europe and will offer the possibility to verify results of former cohort analyses. Thus, MeDALL can become the starting point to stringently plan, conduct and support future common asthma and allergy research initiatives in Europe.
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Publication type Article: Journal article
Document type Scientific Article
Keywords European Birth Cohorts ; Asthma Allergy ; Questionnaire Assessment ; Harmonization ; Medall; Atopic Diseases; Position Paper; Ga(2)len; Children; Childhood; Consumption; Validation; Symptoms
Language english
Publication Year 2014
HGF-reported in Year 2014
ISSN (print) / ISBN 1018-2438
e-ISSN 1423-0097
Journal International Archives of Allergy and Immunology
Quellenangaben Volume: 163, Issue: 3, Pages: 215-224 Article Number: , Supplement: ,
Publisher Karger
Publishing Place Basel ; Freiburg [Breisgau] ; Paris ; London ; New York ; Bangalore ; Bangkok ; Singapore ; Tokyo ; Sydney
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)
POF-Topic(s) 30503 - Chronic Diseases of the Lung and Allergies
Research field(s) Genetics and Epidemiology
PSP Element(s) G-503900-001
PubMed ID 24642608
DOI 10.1159/000357732
WOS ID WOS:000333866600009
Scopus ID 84895931582
Erfassungsdatum 2014-03-28
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