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Imaging the small animal cardiovascular system in real-time with multispectral optoacoustic tomography.
Proc. SPIE 7899:789913 (2011)
Publ. Version/Full Text
DOI
Multispectral Optoacoustic Tomography (MSOT) is an emerging technique for high resolution macroscopic imaging with optical and molecular contrast. We present cardiovascular imaging results from a multi-element real-time MSOT system recently developed for studies on small animals. Anatomical features relevant to cardiovascular disease, such as the carotid arteries, the aorta and the heart, are imaged in mice. The system's fast acquisition time, in tens of microseconds, allows images free of motion artifacts from heartbeat and respiration. Additionally, we present in-vivo detection of optical imaging agents, gold nanorods, at high spatial and temporal resolution, paving the way for molecular imaging applications.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Molecular Imaging ; Optical Imaging ; Optoacoustic Tomography ; Photoacoustic Imaging ; Small Animal Imaging
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
Conference Title
Photons Plus Ultrasound: Imaging and Sensing 2011
Conference Date
January 22, 2011
Conference Location
San Francisco, California, USA
Journal
Proceedings of SPIE
Quellenangaben
Volume: 7899,
Article Number: 789913
Publisher
SPIE
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)