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Hybrid multiphoton and optoacoustic microscope.
Opt. Lett. 39, 1819-1822 (2014)
We present a hybrid microscope combining multiphoton microscopy incorporating second-harmonic generation contrast and optical-resolution optoacoustic (photoacoustic) microscopy. We study the relative performance of the two systems and investigate the complementarity of contrast by demonstrating the label-free imaging capabilities of the hybrid microscope on zebrafish larvae ex vivo, concurrently visualizing the fish musculature and melanocytes. This implementation can prove useful in multiparametric microscopy studies, enabling broader information to be collected from biological specimens.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Photoacoustic Microscopy; Optical Coherence; In-vivo; Tomography; Proteins; Neurons
ISSN (print) / ISBN
0146-9592
e-ISSN
1539-4794
Journal
Optics Letters
Quellenangaben
Volume: 39,
Issue: 7,
Pages: 1819-1822
Publisher
Optical Society of America (OSA)
Publishing Place
Washington
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)