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Open Access Green as soon as Postprint is submitted to ZB.
Video-rate optical flow corrected intraoperative functional fluorescence imaging.
J. Biomed. Opt. 19:46012 (2014)
ABSTRACT. Intraoperative fluorescence molecular imaging based on targeted fluorescence agents is an emerging approach to improve surgical and endoscopic imaging and guidance. Short exposure times per frame and implementation at video rates are necessary to provide continuous feedback to the physician and avoid motion artifacts. However, fast imaging implementations also limit the sensitivity of fluorescence detection. To improve on detection sensitivity in video rate fluorescence imaging, we considered herein an optical flow technique applied to texture-rich color images. This allows the effective accumulation of fluorescence signals over longer, virtual exposure times. The proposed correction scheme is shown to improve signal-to-noise ratios both in phantom experiments and in vivo tissue imaging.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Fluorescence ; Infrared ; Motion ; Real-time Imaging; Indocyanine Green; Localization; Vision; Cancer; Era
ISSN (print) / ISBN
1083-3668
e-ISSN
1560-2281
Journal
Journal of Biomedical Optics
Quellenangaben
Volume: 19,
Issue: 4,
Article Number: 46012
Publisher
SPIE
Publishing Place
Bellingham
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)