Hybrid FMT/XCT system validated with ex-vivo fluorescence.
In: Asia Communications and Photonics Conference and Exhibition (European Conference on Biomedical Optics, ECBO 2009, 14. - 18. Juni 2009, Munich; Germany). Washington, DC: Optical Society of America, 2009.:TuCC2
Fluorescence tomography can resolve fluorescence biodistribution in vivo with high sensitivity. We use structural information from X-ray CT as priors in the fluorescence reconstruction for improved accuracy, as shown previously [1]. The method was tested on different phantoms and animal models and cross-validated with XCT data, histology and ex vivo fluorescence.