Integrated enrichment analysis and pathway-centered visualization of metabolomics, proteomics, transcriptomics, and genomics data by using the InCroMAP software.
J. Chromatogr. B 966, 77-82 (2014)
In systems biology, the combination of multiple types of omics data, such as metabolomics, proteomics, transcriptomics, and genomics, yields more information on a biological process than the analysis of a single type of data. Thus, data from different omics platforms is usually combined in one experimental setup to obtain insight into a biological process or a disease state. Particularly high accuracy metabolomics data from modern mass spectrometry instruments is currently more and more integrated into biological studies. Reflecting this trend, we extended InCroMAP, a data integration, analysis and visualization tool for genomics, transcriptomics, and proteomics data. Now, the tool is able to perform an integrated enrichment analysis and pathway-based visualization of multi-omics data and thus, it is suitable for the evaluation of comprehensive systems biology studies.
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Publication type
Article: Journal article
Document type
Scientific Article
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Keywords
Enrichment Analysis ; Genomics ; Metabolomics ; Pathway Visualization ; Proteomics ; Transcriptomics; Web-based Tool; Knowledgebase
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Language
english
Publication Year
2014
Prepublished in Year
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2014
ISSN (print) / ISBN
1570-0232
e-ISSN
1873-376X
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Volume: 966,
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Pages: 77-82
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Elsevier
Publishing Place
Amsterdam
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Reviewing status
Peer reviewed
POF-Topic(s)
90000 - German Center for Diabetes Research
Research field(s)
Genetics and Epidemiology
Helmholtz Diabetes Center
PSP Element(s)
G-501900-065
G-502400-001
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Erfassungsdatum
2014-05-10