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Eichner, J.* ; Rosenbaum, L.* ; Wrzodek, C.* ; Häring, H.-U. ; Zell, A.* ; Lehmann, R.

Integrated enrichment analysis and pathway-centered visualization of metabolomics, proteomics, transcriptomics, and genomics data by using the InCroMAP software.

J. Chromatogr. B 966, 77-82 (2014)
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In systems biology, the combination of multiple types of omics data, such as metabolomics, proteomics, transcriptomics, and genomics, yields more information on a biological process than the analysis of a single type of data. Thus, data from different omics platforms is usually combined in one experimental setup to obtain insight into a biological process or a disease state. Particularly high accuracy metabolomics data from modern mass spectrometry instruments is currently more and more integrated into biological studies. Reflecting this trend, we extended InCroMAP, a data integration, analysis and visualization tool for genomics, transcriptomics, and proteomics data. Now, the tool is able to perform an integrated enrichment analysis and pathway-based visualization of multi-omics data and thus, it is suitable for the evaluation of comprehensive systems biology studies.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Enrichment Analysis ; Genomics ; Metabolomics ; Pathway Visualization ; Proteomics ; Transcriptomics; Web-based Tool; Knowledgebase
Language english
Publication Year 2014
HGF-reported in Year 2014
ISSN (print) / ISBN 1570-0232
e-ISSN 1873-376X
Quellenangaben Volume: 966, Issue: , Pages: 77-82 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Amsterdam
Reviewing status Peer reviewed
POF-Topic(s) 90000 - German Center for Diabetes Research
Research field(s) Genetics and Epidemiology
Helmholtz Diabetes Center
PSP Element(s) G-501900-065
G-502400-001
PubMed ID 24811976
Erfassungsdatum 2014-05-10