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Tamayo, T.* ; Claessen, H.* ; Rückert, I.-M. ; Maier, W. ; Schunk, M. ; Meisinger, C. ; Mielck, A. ; Holle, R. ; Thorand, B. ; Narres, M.* ; Moebus, S.* ; Mahabadi, A.A.* ; Pundt, N.* ; Krone, B.* ; Slomiany, U.* ; Erbel, R.* ; Jöckel, K.-H.* ; Rathmann, W.* ; Icks, A.*

Treatment pattern of type 2 diabetes differs in two German regions and with patients' socioeconomic position.

PLoS ONE 9:e99773 (2014)
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BACKGROUND: Diabetes treatment may differ by region and patients' socioeconomic position. This may be particularly true for newer drugs. However, data are highly limited. METHODS: We examined pooled individual data of two population-based German studies, KORA F4 (Cooperative Health Research in the Region of Augsburg, south), and the HNR (Heinz Nixdorf Recall study, west) both carried out 2006 to 2008. To ascertain the association between region and educational level with anti-hyperglycemic medication we fitted poisson regression models with robust error variance for any and newer anti-hyperglycemic medication, adjusting for age, sex, diabetes duration, BMI, cardiovascular disease, lifestyle, and insurance status. RESULTS: The examined sample comprised 662 participants with self-reported type 2 diabetes (KORA F4: 83 women, 111 men; HNR: 183 women, 285 men). The probability to receive any anti-hyperglycemic drug as well as to be treated with newer anti-hyperglycemic drugs such as insulin analogues, thiazolidinediones, or glinides was significantly increased in southern compared to western Germany (prevalence ratio (PR); 95% CI: 1.12; 1.02-1.22, 1.52;1.10-2.11 respectively). Individuals with lower educational level tended to receive anti-hyperglycemic drugs more likely than their better educated counterparts (PR; 95% CI univariable: 1.10; 0.99-1.22; fully adjusted: 1.10; 0.98-1.23). In contrast, lower education was associated with a lower estimated probability to receive newer drugs among those with any anti-hyperglycemic drugs (PR low vs. high education: 0.66; 0.48-0.91; fully adjusted: 0.68; 0.47-0.996). CONCLUSIONS: We found regional and individual social disparities in overall and newer anti-hyperglycemic medication which were not explained by other confounders. Further research is needed.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Heinz Nixdorf Recall; European Countries; Southern Germany; Household Income; Prevalence; Health; Care; Inequalities; Management; Mellitus
Language english
Publication Year 2014
HGF-reported in Year 2014
ISSN (print) / ISBN 1932-6203
Journal PLoS ONE
Quellenangaben Volume: 9, Issue: 6, Pages: , Article Number: e99773 Supplement: ,
Publisher Public Library of Science (PLoS)
Publishing Place Lawrence, Kan.
Reviewing status Peer reviewed
Institute(s) Institute of Health Economics and Health Care Management (IGM)
Institute of Epidemiology (EPI)
POF-Topic(s) 30202 - Environmental Health
90000 - German Center for Diabetes Research
Research field(s) Genetics and Epidemiology
PSP Element(s) G-505300-002
G-505300-001
G-504000-006
G-504000-002
G-501900-401
G-504090-001
PubMed ID 24915157
DOI 10.1371/journal.pone.0099773
WOS ID WOS:000340947700133
Scopus ID 84902668545
Erfassungsdatum 2014-06-12
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