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Cost-of-illness studies of atrial fibrillation: Methodological considerations.

Expert Rev. Pharmacoecon. Outcomes Res. 14, 661-684 (2014)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Atrial fibrillation (AF) is the most common heart rhythm arrhythmia, which has considerable economic consequences. This study aims to identify the current cost-of-illness estimates of AF; a focus was put on describing the studies' methodology. A literature review was conducted. Twenty-eight cost-of-illness studies were identified. Cost-of-illness estimates exist for health insurance members, hospital and primary care populations. In addition, the cost of stroke in AF patients and the costs of post-operative AF were calculated. The methods used were heterogeneous, mostly studies calculated excess costs. The identified annual excess costs varied, even among studies from the USA (∼US$1900 to ∼US$19,000). While pointing toward considerable costs, the cost-of-illness studies' relevance could be improved by focusing on subpopulations and treatment mixes. As possible starting points for subsequent economic studies, the methodology of cost-of-illness studies should be taken into account using methods, allowing stakeholders to find suitable studies and validate estimates.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Atrial Fibrillation ; Cost-of-illness ; Decision Support Technique ; Health Economics ; Review; 5 European Countries; United-states; Economic-evaluation; Lifetime Risk; Budget Impact; Burden; Care; Population; Prevalence; Predictors
ISSN (print) / ISBN 1473-7167
e-ISSN 1744-8379
Quellenangaben Volume: 14, Issue: 5, Pages: 661-684 Article Number: , Supplement: ,
Publisher Taylor & Francis
Publishing Place London
Non-patent literature Publications
Reviewing status Peer reviewed