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Cost-of-illness studies of atrial fibrillation: Methodological considerations.
Expert Rev. Pharmacoecon. Outcomes Res. 14, 661-684 (2014)
Atrial fibrillation (AF) is the most common heart rhythm arrhythmia, which has considerable economic consequences. This study aims to identify the current cost-of-illness estimates of AF; a focus was put on describing the studies' methodology. A literature review was conducted. Twenty-eight cost-of-illness studies were identified. Cost-of-illness estimates exist for health insurance members, hospital and primary care populations. In addition, the cost of stroke in AF patients and the costs of post-operative AF were calculated. The methods used were heterogeneous, mostly studies calculated excess costs. The identified annual excess costs varied, even among studies from the USA (∼US$1900 to ∼US$19,000). While pointing toward considerable costs, the cost-of-illness studies' relevance could be improved by focusing on subpopulations and treatment mixes. As possible starting points for subsequent economic studies, the methodology of cost-of-illness studies should be taken into account using methods, allowing stakeholders to find suitable studies and validate estimates.
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Publication type
Article: Journal article
Document type
Review
Keywords
Atrial Fibrillation ; Cost-of-illness ; Decision Support Technique ; Health Economics ; Review; 5 European Countries; United-states; Economic-evaluation; Lifetime Risk; Budget Impact; Burden; Care; Population; Prevalence; Predictors
ISSN (print) / ISBN
1473-7167
e-ISSN
1744-8379
Quellenangaben
Volume: 14,
Issue: 5,
Pages: 661-684
Publisher
Taylor & Francis
Publishing Place
London
Reviewing status
Peer reviewed