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Schipf, S.* ; Ittermann, T.* ; Tamayo, T.* ; Holle, R. ; Schunk, M. ; Maier, W. ; Meisinger, C. ; Thorand, B. ; Kluttig, A.* ; Greiser, K.H.* ; Berger, K.* ; Müller, G.* ; Moebus, S.* ; Slomiany, U.* ; Icks, A.* ; Rathmann, W.* ; Völzke, H.*

Regional differences in the incidence of self-reported type 2 diabetes in Germany: Results from five population-based studies in Germany (DIAB-CORE Consortium)

J. Epidemiol. Community Health 68, 1088-1095 (2014)

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Background Population-based data are paramount to investigate the long-term course of diabetes, for planning in healthcare and to evaluate the cost-effectiveness of primary prevention. We analysed regional differences in the incidence of self-reported type 2 diabetes mellitus in Germany. Methods Data of participants (baseline age 45–74 years) from five regional population-based studies conducted between 1997 and 2010 were included (mean follow-up 2.2–7.1 years). The incidence of self-reported type 2 diabetes mellitus at follow-up was compared. The incidence rates per 1000 person-years (95% CI) and the cumulative incidence (95% CI) from regional studies were directly standardised to the German population (31 December 2007) and weighted by inverse probability weights for losses to follow-up. Results Of 8787 participants, 521 (5.9%) developed type 2 diabetes mellitus corresponding to an incidence rate of 11.8/1000 person-years (95% CI 10.8 to 12.9). The regional incidence was highest in the East and lowest in the South of Germany with 16.9 (95% CI 13.3 to 21.8) vs 9.3 (95% CI 7.4 to 11.1)/1000 person-years, respectively. The incidence increased with age and was higher in men than in women. Conclusions The incidence of self-reported type 2 diabetes mellitus shows regional differences within Germany. Prevention measures need to consider sex-specific differences and probably can be more efficiently introduced toward those regions in need.

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