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Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
CNS regulation of plasma cholesterol.
Ann. Med. 44, 656-663 (2012)
The incidence of disorders related to the control of energy homeostasis, such as hypertension, diabetes, obesity, and dyslipidemia, has dramatically increased worldwide in the last decades. The central nervous system (CNS) plays a critical role regulating the energy balance, therefore there has been increasing interest in understanding the mechanisms whereby the brain controls peripheral metabolism, in order to develop new potential therapies to treat those disorders. While the involvement of the CNS in development of hypertension, obesity, and diabetes has been thoroughly investigated, less is known about the specific role of the brain in the control of circulating lipids. Here we summarize the evidence linking CNS disorders with dyslipidemia, as well as the central mechanisms that directly influence plasma cholesterol.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2012
HGF-reported in Year
0
ISSN (print) / ISBN
0785-3890
e-ISSN
1365-2060
Journal
Annals of Medicine
Quellenangaben
Volume: 44,
Issue: 7,
Pages: 656-663
Publisher
Informa Healthcare
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Obesity (IDO)
POF-Topic(s)
30201 - Metabolic Health
Research field(s)
Helmholtz Diabetes Center
PSP Element(s)
G-502200-001
PubMed ID
21726126
Erfassungsdatum
2012-12-31