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Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
Dietary sugars: a fat difference.
J. Clin. Invest. 119, 1089-92 (2009)
Coronary heart disease is a major cause of morbidity and mortality in Western societies. The metabolic syndrome, characterized by obesity, insulin resistance, elevated blood pressure, elevated triglycerides, and low levels of high-density lipoprotein cholesterol, confers substantial risk of coronary heart disease. Current pathogenetic models suggest that postprandial hyperlipidemia is one specific metabolic abnormality that is typically associated with increased morbidity. In this issue of the JCI, Stanhope and colleagues demonstrate that consumption of fructose-sweetened but not glucose-sweetened beverages for 10 weeks increases de novo lipid synthesis, promotes dyslipidemia, impairs insulin sensitivity, and increases visceral adiposity in overweight or obese adults (see the related article beginning on page 1322).
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
2009
HGF-reported in Year
0
ISSN (print) / ISBN
0021-9738
e-ISSN
1558-8238
Quellenangaben
Volume: 119,
Issue: 5,
Pages: 1089-92
Publisher
American Society of Clinical Investigation
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Obesity (IDO)
POF-Topic(s)
30201 - Metabolic Health
Research field(s)
Helmholtz Diabetes Center
PSP Element(s)
G-502200-001
PubMed ID
19422101
WOS ID
000265843400011
Erfassungsdatum
2009-05-01