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Zeller, T.* ; Hughes, M.* ; Tuovinen, T.* ; Schillert, A.* ; Conrads-Frank, A.* ; Ruijter, H.D.* ; Schnabel, R.B.* ; Kee, F.* ; Salomaa, V.* ; Siebert, U.* ; Thorand, B. ; Ziegler, A.* ; Breek, H.* ; Pasterkamp, G.* ; Kuulasmaa, K.* ; Koenig, W.* ; Blankenberg, S.*

BiomarCaRE: Rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries.

Eur. J. Epidemiol. 29, 777-790 (2014)

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Open Access Green as soon as Postprint is submitted to ZB.

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Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role towards personalised medicine remains uncertain. Biomarker for Cardiovascular Risk Assessment in Europe (BiomarCaRE) is an European collaborative research project with the primary objective to assess the value of established and emerging biomarkers for cardiovascular risk prediction. BiomarCaRE integrates clinical and epidemiological biomarker research and commercial enterprises throughout Europe to combine innovation in biomarker discovery for cardiovascular disease prediction with consecutive validation of biomarker effectiveness in large, well-defined primary and secondary prevention cohorts including over 300,000 participants from 13 European countries. Results from this study will contribute to improved cardiovascular risk prediction across different European populations. The present publication describes the rationale and design of the BiomarCaRE project.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords Biomarcare ; Biomarker ; Cardiovascular Risk Assessment ; Eu ; Morgam; Coronary-artery-disease; Cardiovascular-disease; Myocardial-infarction; Vascular Events; Risk; Biomarkers; Prediction; Protein; Prognosis; Discovery

ISSN (print) / ISBN 0393-2990

e-ISSN 1573-7284

Journal European Journal of Epidemiology

Quellenangaben Volume: 29, Issue: 10, Pages: 777-790

Publisher Springer

Publishing Place Dordrecht

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Epidemiology II (EPI2)