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Heyder, I.R. ; Pohlit, W.

Proliferation of lethally damaged mammalian cells irradiated by fast electrons, fast neutrons, α particles, and pions.

Radiat. Res. 82, 352-363 (1980)
Publ. Version/Full Text To article DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Proliferation of lethally damaged tumor cells was determined after irradiation with fast electrons, fast neutrons, α particles, and pions in the peak and plateau of the depth dose curve. The method used was measurement of the proliferation of the total population, N(tot), and the subpopulation of viable cells which are able to grow to macrocolonies after irradiation, N(m). The difference between these populations (N(tot) - N(m)) then represents the lethally damaged cells. The number of cell divisions after irradiation decreases with increasing absorbed dose in the same way for all the different types of radiation if related to the survival of cells, S. Consequences for the type of lethal radiation damage in mammalian cells and for radiotherapy are discussed.
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Publication type Article: Journal article
Document type Scientific Article
Language english
Publication Year 1980
HGF-reported in Year 0
ISSN (print) / ISBN 0033-7587
e-ISSN 1938-5404
Journal Radiation Research
Quellenangaben Volume: 82, Issue: 2, Pages: 352-363 Article Number: , Supplement: ,
Publisher Radiation Research Society
Reviewing status Peer reviewed
Institute(s) Department of Radiation Sciences (DRS)
PubMed ID 7375637
DOI 10.2307/3575385
Permalink http://www.jstor.org/discover/10.2307/3575385?uid=3737864&uid=2&uid=4&sid=21104518261231
Scopus ID 0018823909
Erfassungsdatum 1980-07-17
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