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Open Access Green as soon as Postprint is submitted to ZB.
Induction of cALL antigen and terminal deoxynucleotidyltransferase in normal peripheral lymphocyte during PHA stimulation.
Leuk. Res. 6, 421-423 (1982)
In PHA cultures of peripheral lymphocytes from three healthy donors the extent and time sequence of cALL and TdT positivity was followed over a period of seven days. In all cases significant percentages of cALL + and TdT + cells were observed. However, the period of positivity for both these markers tended to be short. In contrast to previous results with the diffusion chamber system which yielded a comparatively uniform pattern of positivity, PHA cultures of the present cases revealed a more heterogeneous pattern concerning the extent as well as the time sequence of positivity. These experiments provide a broader basis for the notion that those markers are expressed during blastogenesis of normal lymphocytes which are generally regarded as indicative of early lymphatic differentiation and of the stage of developmental arrest of acute lymphatic leukemias.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0145-2126
e-ISSN
1873-5835
Journal
Leukemia Research
Quellenangaben
Volume: 6,
Issue: 3,
Pages: 421-423
Publisher
Elsevier
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institut für Hämatologie