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Veronese, I.* ; Cantone, M.C.* ; Giussani, A.* ; Maggioni, T.* ; Birattari, C.* ; Bonardi, M.L.* ; Groppi, F.* ; Garlaschelli, L. ; Werner, E. ; Roth, P. ; Höllriegl, V. ; Louvat, P. ; Felgenhauer, N.* ; Zilker, T.H.*

Stable tracer investigations in humans for assessing the biokenetics of ruthenium and zirconium radionuclides.

Radiat. Prot. Dosim. 105, 209-212 (2003)
Open Access Green as soon as Postprint is submitted to ZB.
The interest in the biokinetics of ruthenium and zirconium in humans is justified by the potential radiological risk represented by their radionuclides. Only a few data related to the biokinetics of ruthenium and zirconium in humans are available and, accordingly, the biokinetic models currently recommended by the ICRP for these elements are mainly based on data from animal experiments. The use of stable isotopes as tracers, coupled with a proper analytical technique (nuclear activation analysis with protons) for their determination in biological samples, represents an ethically acceptable methodology for biokinetic investigations, being free from any radiation risk for the volunteer subjects. In this work, the results obtained in eight biokinetic investigations for ruthenium, conducted on a total of three healthy volunteers, and six for zirconium, performed on a total of three subjects, are presented and compared to the predictions of the ICRP models.
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Publication type Article: Journal article
Document type Scientific Article
ISSN (print) / ISBN 0144-8420
e-ISSN 1742-3406
Journal Radiation Protection Dosimetry
Quellenangaben Volume: 105, Issue: 1-4, Pages: 209-212 Article Number: , Supplement: ,
Publisher Oxford University Press
Publishing Place Oxford
Reviewing status Peer reviewed
Institute(s) Institute of Radiation Protection (ISS)