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Open Access Green as soon as Postprint is submitted to ZB.
Distribution of s1-nuclease sensitive sites and double-Strand breaks in γ-irradiated λ-DNA.
Int. J. Radiat. Biol. 46, 675-679 (1984)
Double-strand breaks and regions with unpaired bases (S1-nuclease sensitive sites) are formed in the DNA of γirradiated λphages. The frequency of both events was determined in the various fragments produced after digestion with a restriction enzyme (Eco RI). The results show that both types of radiation damage are randomly distributed in the DNA molecule. There is no hint that the S1 sites are formed in preferred regions of the λgenome.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Base Damage ; Double-strand Breaks ; S1-nuclease ; λphage
ISSN (print) / ISBN
0955-3002
e-ISSN
1362-3095
Quellenangaben
Volume: 46,
Issue: 6,
Pages: 675-679
Publisher
Informa Healthcare
Reviewing status
Peer reviewed
Institute(s)
Abteilung für Strahlenbiologie und Biophysik