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Distribution of s1-nuclease sensitive sites and double-Strand breaks in γ-irradiated λ-DNA.

Int. J. Radiat. Biol. 46, 675-679 (1984)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
Double-strand breaks and regions with unpaired bases (S1-nuclease sensitive sites) are formed in the DNA of γirradiated λphages. The frequency of both events was determined in the various fragments produced after digestion with a restriction enzyme (Eco RI). The results show that both types of radiation damage are randomly distributed in the DNA molecule. There is no hint that the S1 sites are formed in preferred regions of the λgenome.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Base Damage ; Double-strand Breaks ; S1-nuclease ; λphage
ISSN (print) / ISBN 0955-3002
e-ISSN 1362-3095
Quellenangaben Volume: 46, Issue: 6, Pages: 675-679 Article Number: , Supplement: ,
Publisher Informa Healthcare
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Abteilung für Strahlenbiologie und Biophysik