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The relationship between cisplatin sensitivity and drug uptake into mammalian cells in vitro.

Br. J. Cancer 54, 239-243 (1986)
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Clonogenic survival of HeLa, Chinese hamster and HaK cells after treatment with a range of cisplatin concentrations and exposure times was determined and cellular platinum concentrations were measured by PIXE. It was demonstrated that cisplatin cytotoxicity of the three cell lines varied considerably as a function of drug exposure dose. These differences are related to differential cellular drug uptake.
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Publication type Article: Journal article
Document type Scientific Article
Language english
Publication Year 1986
HGF-reported in Year 0
ISSN (print) / ISBN 0007-0920
e-ISSN 1532-1827
Quellenangaben Volume: 54, Issue: 2, Pages: 239-243 Article Number: , Supplement: ,
Publisher Nature Publishing Group
Reviewing status Peer reviewed
Institute(s) Physikalisch-Technische Abteilung
PubMed ID 3741760
Scopus ID 0022504572
Erfassungsdatum 1986-12-30