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Particle deposition in extrathoracic airways of healthy subjects and of patients with early stages of laryngeal carcinoma.

J. Aerosol Sci. 15, 215-217 (1983)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
The human respiratory tract can be divided into an extrathoracic, a bronchial and an alveolar region. Knowledge of the deposition of inhaled aerosol particles in these regions (regional deposition) can be used to estimate the health risk connected with the inhalation of atmospheric pollutants. For the determination of regional deposition, radioactively labeled aerosol particles are inhaled through the mouth, and the deposited particles in the respiratory tract are detected by the radiotracer method as described elsewhere. In this paper, attention is focused on deposition in the extrathoracic region. Particles with aerodynamic diameters smaller than 2 mu m pass the extrathoracic region (pharynx, larynx, and 3 cm of the upper end of the trachea) without being deposited. For larger particles, this region has been shown to be an effective aerosol filter, the efficiency of which increases with the flow rate of the aerosol (impaction).
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0021-8502
e-ISSN 1879-1964
Quellenangaben Volume: 15, Issue: 3, Pages: 215-217 Article Number: , Supplement: ,
Publisher Elsevier
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Departments & Institutes