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Fluorescent protein imaging with multispectral optoacoustic tomography.
Proc. SPIE 7564:75641R (2010)
Publ. Version/Full Text
DOI
In this work, we have developed a selective-plane illumination multispectral optoacoustic tomography (MSOT) technique for high-resolution whole-body visualization of intact optically diffusive organisms whose sizes may vary from sub-millimeter up to a centimeter range and beyond. By combining multi-wavelength illumination, the method is shown capable of resolving tissue-specific expression of fluorescent proteins and other molecular biomarkers located deep in living optically diffuse tissues.
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Publication type
Article: Journal article
Document type
Scientific Article
Editors
Oraevsky, A. A.* ; Wang, L.V.*
Keywords
Fluorescent proteins; Optoacoustic; Molecular imaging; Small animals; Photoacoustic tomography
Language
english
Publication Year
2010
HGF-reported in Year
0
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
Journal
Proceedings of SPIE
Quellenangaben
Volume: 7564,
Article Number: 75641R
Publisher
SPIE
Publishing Place
Bellingham, WA
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-505500-001
Erfassungsdatum
2010-07-28