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as soon as is submitted to ZB.
Itching to end NF-kB.
Nat. Immunol. 9, 227-229 (2008)
Both activation and termination of transcription factor NF-kB signaling require ubiquitin modification of pathway components. The E3 ligase Itch teams up with the NF-kB inhibitor A20 to edit the composition of ubiquitin chains on the signaling adaptor RIP, thereby limiting inflammatory responses.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
1529-2908
e-ISSN
1529-2916
Journal
Nature Immunology
Quellenangaben
Volume: 9,
Issue: 3,
Pages: 227-229
Publisher
Nature Publishing Group
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Research Unit Molecular Immune Regulation (AMIR)