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Open Access Green as soon as Postprint is submitted to ZB.
Experimental data for total deposition in the respiratory tract of children.
Toxicol. Lett. 72, 137-144 (1994)
Up to now only few experimental data for total deposition of inhaled aerosol particles are available for children. In this study 29 healthy children aged between 3 and 14 years volunteered for the determination of 1 μm, 2 μm and 3 μm particles for spontaneous and controlled breathing. It turns out that total deposition values for children are higher than for adults.The effect is significant for all particle sizes (Kruskal-Wallis). For the applied breathing patterns deposition decreases as a function of body height. For inhalation risk assessments the number of particles deposited per unit time (deposition rate) rather than the deposition per breath has to be taken. During spontaneous breathing at rest the deposition rate is on average higher for children than for adults.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Controlled Breathing ; Spontaneous Breathing ; Total Deposition Data For Children
ISSN (print) / ISBN
0378-4274
e-ISSN
1879-3169
Journal
Toxicology Letters
Quellenangaben
Volume: 72,
Issue: 1-3,
Pages: 137-144
Publisher
Elsevier
Publishing Place
Amsterdam
Reviewing status
Peer reviewed
Institute(s)
Institut für Inhalationsbiologie