Microwaves near 42 GHz are found to influence the growth of Saccharomyces cerevisiae. The growth is measured photometrically in stirred aqueous culture. The microwave effect occurs and saturates above a threshold intensity < 10 mW/cm2, excluding any explanation based on microwave heating. A surprisingly strong frequency dependence is observed, with resonances as narrow as 8 MHz. These results confirm the existence of a nonthermal resonant microwave sensitivity in biology; they suggest yet unknown tuned systems triggering yet unknown biological actions.