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Open Access Green as soon as Postprint is submitted to ZB.
Simulation of genetic networks modelled by piecewise deterministic Markov processes.
IET Syst. Biol. 2, 113-135 (2008)
The authors propose piecewise deterministic Markov processes as an alternative approach to model gene regulatory networks. A hybrid simulation algorithm is presented and discussed, and several standard regulatory modules are analysed by numerical means. It is shown that despite of the partial simplification of the mesoscopic nature of regulatory networks such processes are suitable to reveal the intrinsic noise effects because of the low copy numbers of genes.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
1751-8849
e-ISSN
1751-8857
Journal
IET Systems Biology
Quellenangaben
Volume: 2,
Issue: 3,
Pages: 113-135
Publisher
Institution of Engineering and Technology (IET)
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biomathematics and Biometry (IBB)