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Whiteley, A.S.* ; Manefield, M.* ; Lüders, T.

Unlocking the 'microbial black box' using RNA-based stable isotope probing technologies.

Curr. Opin. Biotechnol. 17, 67-71 (2006)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Microbial ecologists have long sought to associate the transformation of compounds in the environment with the microbial clades responsible. The development of stable isotope probing (SIP) has made this possible in many ecological and biotechnological contexts. RNA-based SIP technologies represent a significant leap forward for culture-independent 'functional phylogeny' analyses, where specific consumption of a given compound carrying a (13)C signature can be associated with the small subunit ribosomal RNA molecules of the microbes that consume it. Recent advances have led to the unequivocal identification of microorganisms responsible for contaminant degradation in engineered systems, and to applications enhancing our understanding of carbon flow in terrestrial ecosystems.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0958-1669
e-ISSN 1879-0429
Quellenangaben Volume: 17, Issue: 1, Pages: 67-71 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Amsterdam
Non-patent literature Publications
Reviewing status Peer reviewed