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Open Access Green as soon as Postprint is submitted to ZB.
Antibiotic treatment of community acquired pneumonia varies widely across Germany.
J. Infect. 54, 446-453 (2007)
Community Acquired Pneumonia (CAP) is a frequent and potentially fatal infectious disease which, in the majority of cases, needs an antibiotic intervention.Objectives: Aim was to evaluate antibiotic treatment patterns regarding all types of mono- and combination-therapy throughout the local clinical centres (LCCs) represented in the German competence network CAPNETZ (= Community Acquired Pneumonia Network) and to identify clinical indicators for regional differences.Methods: We analysed outpatients and inpatients recruited between March 2003 and April 2005. Patient and treatment details were registered online using standardised data entry forms. A logistic regression model was issued for the 4 most frequently applied antibiotics, adjusting for potentially relevant confounders.Results: The study sample consisted of 3221 patients at the age of 18 to 102 years. Overall, aminopenicillins plus betalactamase inhibitor (20.4%), fluoroquinolone (17.0%), macrolides combined with cephalosporins third generation (10.6%) and cephalosporins third generation (8.9%) were most frequently prescribed. After control for potential confounders, significant treatment differences remained between study sites.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
antibiotic treatment; community acquired pneumonia; treatment patterns
ISSN (print) / ISBN
0163-4453
e-ISSN
0163-4453
Journal
Journal of Infection
Quellenangaben
Volume: 54,
Issue: 5,
Pages: 446-453
Publisher
Elsevier
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Epidemiology I (EPI)