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Vierling, W.* ; Stampfl, A.

Magnesium-dependent calcium efflux in mammalian heart muscle.

Cell Calcium 15, 175-182 (1994)
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Extra and intracellular magnesium is involved in the control of myocardial calcium movements. Here we report on an increase in cytosolic calcium concentration in resting ventricular myocytes due to the withdrawal of extracellular magnesium under the condition of a blocked sodium-dependent calcium elimination. Evidence for an activation of cellular calcium efflux by extracellular magnesium showed experiments in perfused hearts. It is concluded that extracellular magnesium can modulate the intracellular free calcium concentration of the myocardial cell by its influence on calcium elimination.
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Publication type Article: Journal article
Document type Scientific Article
Language english
Publication Year 1994
HGF-reported in Year 0
ISSN (print) / ISBN 0143-4160
e-ISSN 1532-1991
Journal Cell calcium
Quellenangaben Volume: 15, Issue: 2, Pages: 175-182 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Amsterdam
Reviewing status Peer reviewed
Institute(s) Institut für Toxikologie
PubMed ID 8149417
DOI 10.1016/0143-4160(94)90056-6
Scopus ID 0027979968
Erfassungsdatum 1994-02-15
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