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Vierling, W.* ; Stampfl, A.

Magnesium-dependent calcium efflux in mammalian heart muscle.

Cell Calcium 15, 175-182 (1994)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Extra and intracellular magnesium is involved in the control of myocardial calcium movements. Here we report on an increase in cytosolic calcium concentration in resting ventricular myocytes due to the withdrawal of extracellular magnesium under the condition of a blocked sodium-dependent calcium elimination. Evidence for an activation of cellular calcium efflux by extracellular magnesium showed experiments in perfused hearts. It is concluded that extracellular magnesium can modulate the intracellular free calcium concentration of the myocardial cell by its influence on calcium elimination.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0143-4160
e-ISSN 1532-1991
Journal Cell calcium
Quellenangaben Volume: 15, Issue: 2, Pages: 175-182 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Amsterdam
Non-patent literature Publications
Reviewing status Peer reviewed