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Open Access Green as soon as Postprint is submitted to ZB.
Downregulation of messenger RNA levels for ribosomal proteins in differentiating HL-60 cells.
Exp. Cell Res. 200, 145-148 (1992)
After differentiation induction in HL-60 cells by treatment with retinoic acid, phorbol ester, or dimethyl sulfoxide strong downregulation of the steady state mRNA level of the putative protein No. 3 of the large ribosomal subunit (rpL3) was observed. Downregulation was also observed in other hemopoietic human cell lines, although to a lesser extent. Four ribosomal protein mRNAs were compared in their degree of downregulation after differentiation induction or actinomycin D treatment. The comparatively fast response of rpL3 mRNA observed could indicate a regulatory function of rpL3 protein.
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
1090-2422
e-ISSN
0014-4827
Journal
Experimental Cell Research
Quellenangaben
Volume: 200,
Issue: 1,
Pages: 145-148
Publisher
Academic Press
Publishing Place
Orlando, Fla.
Non-patent literature
Publications
Reviewing status
Peer reviewed