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Toxicity tests with luminescent photobacteria and quantitative structure activity relationships for nitroparaffins.
Chemosphere 24, 1835-1843 (1992)
EC50 values of different nitroparaffins were determined by a photobacterium phosphoreum toxicity test. Octanol/water partition coefficients were determined by a reversed phase HPLC method. From these experimental data quantitative structure activity relationships were deduced which point to a dependence of toxicity on a 'form factor' that includes the number of methyl and methylene groups in a molecule. The hypothesis will be formulated that the specific effects depend on the number of methylgroups and an equation for specific effects is given
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Publication type
Article: Journal article
Document type
Scientific Article
ISSN (print) / ISBN
0045-6535
e-ISSN
1879-1298
Journal
Chemosphere
Quellenangaben
Volume: 24,
Issue: 12,
Pages: 1835-1843
Publisher
Elsevier
Publishing Place
Kidlington, Oxford
Reviewing status
Peer reviewed
Institute(s)
PPM-MEX-Molecular EXposomics (MEX)
Institute of Ecological Chemistry (IOEC)
Institute of Ecological Chemistry (IOEC)