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Ahlborg, U.G.* ; Brouwer, A.* ; Fingerhut, M.A.* ; Jacobson, J.L.* ; Jacobson, S.W.* ; Kennedy, S.W.* ; Kettrup, A. ; Koeman, J.H.* ; Poiger, H.* ; Rappe, C.* ; Safe, S.H.* ; Seegal, R.F.* ; Tuomisto, J.* ; Van Den Berg, M.D.*

Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept.

Eur. J. Pharmacol. 228, 179-199 (1992)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
A scientific evaluation was made of the mechanisms of action of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls. Distinction is made between the aryl-hydrocarbon (Ah) receptor-mediated and non-Ah receptor-mediated toxic responses. Special attention is paid to the applicability of the toxic equivalency factor (TEF) concept.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords (pcbs) ; (pcdds) ; (pcdfs) ; (tef) ; Ah (aryl-hydrocarbon)-mediated Effects ; Ah Receptors ; Carcinogenicity ; Endocrine Responses ; Kinetics ; Metabolism ; Neurobehavioural Responses ; Non-ah (aryl-hydrocarbon)-mediated Effects ; Polychlorinated Biphenyls ; Polychlorinated Dibenzo-p-dioxins ; Polychlorinated Dibenzofurans ; Risk Management ; Species Differences ; Toxic Equivalency Factor
ISSN (print) / ISBN 0014-2999
e-ISSN 0014-2999
Journal European Journal of Pharmacology
Quellenangaben Volume: 228, Issue: 4, Pages: 179-199 Article Number: , Supplement: ,
Publisher Elsevier
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Ecological Chemistry (IOEC)