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Hoffmann-Fezer, G. ; Hoffmann, R.M.*

Anatomical distribution of T- and B-lymphocytes in Marek's disease - An immunohistochemical study.

Vet. Immunol. Immunopathol. 1, 113-123 (1980)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
Neural lesions of Marek's disease, Marek's disease tumours in the ovary, liver, and kidney, as well as spleen and bursa of Fabricii of chickens bearing Marek's disease tumorous infiltrations, were examined by a new immunohistochemical technique basing upon Sternbergers unlabelled antibody enzyme method which allows the exact localization of lymphoid cells based on their surface antigens. Type C neural lesions contained T-lymphocytes almost exclusively. Type B neural lesions had relatively high proportions of T- and B-lymphocytes, and severe type A neural lesions possessed one part of heavily labelled T-lymphocytes and a number of cells stained weakly by rabbit-antichicken-T-cell-globulin. Tumorous infiltrations had similar characteristics as type A neural lesions. Spleen and interfollicular spaces of bursa of Fabricius were infiltrated by T-lymphocytes.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
ISSN (print) / ISBN 0165-2427
e-ISSN 1873-2534
Quellenangaben Volume: 1, Issue: 2, Pages: 113-123 Article Number: , Supplement: ,
Publisher Elsevier
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institut für Hämatologie